Lee Harvey's Target Range

Mandiant Red Curtain
http://www.mandiant.com/mrc

A tool to manually scan folders or files for suspicious criteria, such as entropy/randomness, binary packing, compiler signatures, digital signatures, and other characteristics that generate an overall threat score. While not fool-proof, it does find some interesting files -- especially on computers used by kids.

Note: Mandiant Red Curtain requires Microsoft .NET Framework 2.0

BTW, to obtain a sanity check of Mandiant's file scoring, submit individual file samples (those marked red in Mandiant with high scores) to...

VirusTotal
http://www.virustotal.com/

...which further scans them using 32 separate virus scanning engines with their latest signature DATs.

Note: Opera binaries are packed using ASPack, and are not digitally signed with a code-signing certificate, which apparently qualifies them as yellow in Mandiant. Obviously, you can ignore Mandiant's ranking of Opera binaries.

Enjoy.