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Musings

Bringing things into focus

A big step forward toward Ray Kurzweil’s ‘Singularity’

I read a news release today from UCLA that reported a major advance in our understanding of how memories are formed. According to the report, the researchers used a fluorescent protein that can change from green to red when exposed to ultraviolet light. They flashed the cells with light, so that any proteins that already existed turned red. But when the scientists induced the cells to form memories, they saw new green proteins appear under the microscope.

Interestingly, the new proteins were created on both sides of a given synapse, and the affected synapses were not contiguous, but appeared to form a random pattern in the brain. Unlike a computer, the brain appears to do its thing by manipulating such patterns to form thoughts and perform computations. By distributing the stored patterns across the brain structure in a seemingly random way, nature has provided us with some protection if a specific region of the brain is disabled or damaged. This is absolutely amazing to me, and it made me think about the near-term potential for artificially reprogramming the brain.

This means creating memories of events that never happened, or inducing ‘education’ without the need to study or attend lectures. You become an instant expert in any discipline or art. This is accomplished by injecting RNA that is ‘preconfigured’ to create and fold proteins in a specific sequence that would attach to unassigned synaptic junctions.

I can see a likely new discipline that would be hotly pursued: Conditional Psychophysiology. Think about the ability to rehabilitate criminals through ‘reeducation’, the removal of long-term conditioned reflexes due to emotional trauma, or the more Orwellian aspect of making citizens more accepting of social or political philosophies. I have no doubt that such a ‘medical’ technology will be available within the next twenty years.

Like gunpowder or the atom bomb, this enabling technical advance is fraught with immense promise and immense danger as well. In fact, all aspects of the coming ‘Singularity’ are bipolar in this respect; the greatest danger being the demise of the Human race as it may become supplanted by selfish thinking machines that are more intelligent than we are. Perhaps the ability to ‘flash reprogram’ the Human brain will buy us a little time to deal effectively and fairly with our mechanical progeny.






Unintended consequences at Lawrence Livermore LabsDuke Nukem

Comments

Stardancer 28. June 2009, 02:57

This is scary.

:worried:

David 28. June 2009, 12:24

Hi Stardancer, thanks for reading my blather here.

It could be scary if we don't have a benign social setting and an agreed-upon phase in period for the new technologies.

ERWIN 28. June 2009, 18:59

David

Thats more than scary....

Anonymous 28. June 2009, 19:35

Lil' Bro writes:

I recently heard a lecture at the American Neurological Society which suggested that methylation of DNA may be the mechanism of memory formation. Like stikcing post-it notes on a slinky, the methylation marks specific events, which can be reviewed by unwinding the slinky. Evidence: enzymes which prevent methylation inhibit learning in invertabrates. It would be quite stunning to prove that DNA not only transmits genetic information, but also encodes memories.

David 28. June 2009, 23:45

Hi Lil'Bro, thanks for your lucid comments. The methylation hypothesis is interesting, but only RNA can create the proteins as witnessed. If this mechanism is driving RNA by the DNA as usual, it still would only be a stepping stone to the ultimate destination: long-term memory in the form of proteins.

But then, I am not a scientist; only a former worker in the trenches of the electronics industry. Therefore, I know next to nothing about the subject under discussion. Homer: Doh!

David 28. June 2009, 23:46

Hi Erwin, the future has always been scary.....thanks for the visit! :smile:

David Scott Aubrey 1. July 2009, 02:10

Hmm ... this could also have military applications - inject proteins to enhance the ability to follow orders without question, etc. :left: :right:

Dillon Roberts 1. July 2009, 04:19

Damn, I've been away too long. That's some matrix-like stuff, Dave. I'm glad I just read that. Gonna be recording again soon. Drop by in a couple of weeks.

David 1. July 2009, 12:46

Hi David, you are right, the potential for manipulation is endless.....:spock:

Hi Dillon, thanks for the visit---good to see you back! It could indeed be like the Matrix if we are not careful...:no:

David Scott Aubrey 1. July 2009, 13:56

Hmm ... if we wanted to get really weirded out, we could consider a scenario where 'they' release invisible and odourless proteins into the air to change the behaviour of ... everyone! :eyes:

(Ever see They Live?) :wink:

David 1. July 2009, 19:29

Hi again, David. Airborne proteins would not get absorbed, as they wouldn't make it past the blood/brain barrier. Thanks for the link, I'll check it out. :smile:

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