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This is all a matter of opinion. Sure, McAffe and Norton Desktop products have a bad rep. But some ones that have better status are Norton Corporate (if you try to say ALL Norton products are junk, well then ignorance is bliss.), NOD32, and Zone Alarm/Kaspersky.

None of the "better" ones mentioned above are better than one another, they will do the same job at finding things. If you try to say "Norton didn't find this!!!11!!" then you may want to also note that others won't find things that Norton will.

Honestly, you aren't going to find "the" best anti virus, it's which are good, and which aren't.

As for your computer running "smoother" and "faster", of course it will, you are uninstalling a program that is ALWAYS running. Think about that.

I will be one of the very few that will go unbiased on Anti Virus, most are resource hogs, and uneffective. But I will list several products that I know are good.

I don't mean to put anyone down for their opinion, but most people just go by word of mouth and not investigating what they hear.

Some good anti virus/anti spyware products are:
Windows Live OneCare
Zone Alarm Security Suite Professional
Kaspersky
ESET NOD32
Symantec (Norton) Corporate 10.1 (2k/xp/2003) / 10.2 (Vista/2008)

This is a post I made on a forum about anti virus. This is one of the first real posts I've made in a while and thought I did a good job, so I now share it with you.