macedon - Population History of the Dniester-Carpathians

Population History of the Dniester-Carpathians

Wednesday, 18. July 2007, 21:53:00

ај да се видиме со карпатските народи генетски..

Population History of the Dniester-Carpathians:
Evidence from Alu Insertion and Y-Chromosome
Polymorphisms
Dissertation der Fakultät für Biologie
der Ludwig-Maximilians-Universität München
vorgelegt von
Alexander Varzari
aus Moldawien
27.07.2006

1 SUMMARY
The Dniester-Carpathian region has attracted much attention from historians, linguists, and
anthropologists, but remains insufficiently studied genetically. We have analyzed a set of
autosomal polymorphic loci and Y-chromosome markers in six autochthonous Dniester-
Carpathian population groups: 2 Moldavian, 1 Romanian, 1 Ukrainian and 2 Gagauz
populations. To gain insight into the population history of the region, the data obtained in
this study were compared with corresponding data for other populations of Western
Eurasia.

The analysis of 12 Alu human-specific polymorphisms in 513 individuals from the
Dniester-Carpathian region showed a high degree of homogeneity among Dniester-
Carpathian as well as southeastern European populations. The observed homogeneity
suggests either a common ancestry of all southeastern European populations or a strong
gene flow between them. Nevertheless, tree reconstruction and principle component
analyses allow the distinction between Balkan-Carpathian (Macedonians, Romanians,
Moldavians, Ukrainians and Gagauzes) and Eastern Mediterranean (Turks, Greeks and
Albanians) population groups. These results are consistent with those from classical and
other DNA markers and are compatible with archaeological and paleoanthropological data.
Haplotypes constructed from Y-chromosome markers were used to trace the paternal
origin of the Dniester-Carpathian populations. A set of 32 binary and 7 STR Ychromosome
polymorphisms was genotyped in 322 Dniester-Carpathian Y-chromosomes.